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Exploring rare potential harms from low-dose CT lung cancer screening to aid decision making - Radiology Business

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Several recent studies have explored the potential benefits of screening for lung cancer with low-dose CT. But what about the potential harms, particularly among minority populations treated at safety-net hospitals?

Philadelphia physicians recently set out to explore these questions, conducting a prospective study including nearly 1,000 patients screened for the disease. They found rare instances of harm, highlighting five example patients whose cases can help inform future discussions, according to a study published Sept. 9 in the Annals of Thoracic Surgery.

In one instance, CT of a 74-year-old Black female patient revealed an 8 mm nodule in the right upper lobe that further imaging confirmed was lung cancer. However, the woman declined treatment until two years later when she experienced discomfort breathing, leading to a biopsy and radiation therapy.

“In-depth discussions about willingness to undergo treatment must be done before screening to avoid scenarios like this,” Lynde Lutzow, MD, with the Department of Surgery at Temple University Health Systems, and colleagues advised. “Levels of mistrust are higher in underserved and minority patients given instances of racism, implicit bias, and microaggressions experienced by these patients in the healthcare system,” they added later. “Specifically, African American lung cancer patients are more likely to decline surgery compared to their White counterparts. Our patient illustrates how clinical care experiences must facilitate trust between clinician and patient to successfully deliver [shared decision making] for [lung cancer screening].”

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Exploring rare potential harms from low-dose CT lung cancer screening to aid decision making - Radiology Business
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